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What is the full name of Rev Erb?
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The ID1 peptide forms an unprecedented anti-parallel β-sheet with Rev-erbα, as well as an α-helix similar to that seen in NR/ID2 crystal structures, but out of ...
... Reverba ligand binding domain bound with an NCoR ID1 peptide determined to 2.60A ... Keywords, Transcription regulator / Reverba NCoRID1 / anti-parallel b-sheet ...
Jun 30, 2010 · The ID1 peptide forms an unprecedented antiparallel beta-sheet with Rev-erbalpha, as well as an alpha-helix similar to that seen in nuclear ...
NRs bind directly to specific DNA response elements in the regulatory region of their target genes and regulate the rate of transcription in a ligand-dependent ...
Structural basis for heme-dependent NCoR binding to the transcriptional ...
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May 7, 2020 · These data indicate that heme stabilizes a REV-ERBβ LBD conformation that alters the NCoR ID1 antiparallel β-sheet binding mode but preserves ...
Feb 19, 2024 · In our study, fibril with a parallel β-sheet structure and oligomer with an anti-parallel β-sheet structure were distinguished based on the ...
Here, we identify the orphan nuclear receptor REV-ERBα as the major regulator of cyclic Bmal1 transcription. Circadian Rev-erbα expression is controlled by ...
Designed peptides that fold autonomously to specific conformations in aqueous solution are useful for elucidating protein secondary structural preferences.
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Oct 13, 2015 · This is a canonical motif in which disulfide-bonded cysteine residues are positioned directly opposite each other on adjacent anti-parallel β- ...